The Church of Psilomethoxin asserts that by mixing the hallucinogenic
substance 5-MeO-DMT, an unique psychedelic drug may be produced.
Members of the Church of
Psilomethoxin
have taken psilomethoxin, a recently produced hybrid psychedelic substance.
The Church of Psilomethoxin's mission is to establish the drug as their
sacrament, bearing the same name as the drug.
The group, which was established in 2021, has amassed a following online
even though nobody knows if their mysterious blend includes anything unique.
But now, as reported by
IFL Science, scientists have tested the material for psilomethoxin signs after
receiving a sample of the medicine from an unknown churchgoer.
The Church of Psilomethoxin asserts that by mixing the substrate of farmed
magic mushrooms with the hallucinogenic molecule 5-MeO-DMT, which naturally
exists in the lethal secretions of the Sonoran Desert toad, a unique
psychedelic drug may be produced.
They write
in the study, "This substance, known as psilomethoxin, is supposed to have unique
features and effects compared to standard psychedelics."
They were motivated by Alexander "Sasha" Shulgin.
They assert that the concept for this procedure came from the well-known
American scientist Alexander "Sasha" Shulgin, who is credited with creating
hundreds of psychedelic compounds.
The Church of Psilomethoxin claims that it utilized this method to create
its sacrament in late 2021. Shulgin proposed in 2005 that mixing these two
drugs would result in a hybrid molecule.
As "the hypothesized process for synthesizing psilomethoxin within the
mushrooms defies the known knowledge of psilocybin biosynthesis," the
authors of the most recent preprint paper express doubt.
"No evidence to imply that the substance psilomethoxin is found in samples
of material that the church is giving to their followers online," they
concluded after analyzing their sample using UPLC-HRMS.
As opposed to this, they write, "the sample consists primarily of
recognized tryptamines and other natural compounds anticipated to be present
in dried Psilocybe mushrooms, notably psilocybin and psilocin, with a trace
quantity of baeocystin."
Research Abstract:
The Church of Psilomethoxin asserts that by adding 5-MeO-DMT to the
substrate of farmed Psilocybe mushrooms, psilomethoxin, the church's
sacrament, is produced as a new tryptamine. Using in-depth analytical
methods, such as ultra-performance liquid chromatography with
high-resolution mass spectrometry, we explore the veracity of this assertion
in this work (UPLC-HRMS). For comparison, real reference standards for
structurally comparable tryptamines were employed. Our research found no
proof that the substance psilomethoxin is present in samples of the
literature the church is making available to its adherents online.
Nonetheless, the sample's unmistakable presence of psilocybin, baeocystin,
and psilocin suggests that the statements regarding the production of
psilomethoxin may be incorrect. In light of public health and safety, the
ramifications of these findings need to be carefully evaluated.
